This shows you the differences between two versions of the page.
chemdata:amdisexplained [2014/03/11 17:47] |
chemdata:amdisexplained [2014/03/11 17:47] (current) |
||
---|---|---|---|
Line 1: | Line 1: | ||
+ | ===== Automated Mass Spectral Deconvolution & Identification System ===== | ||
+ | With the support of the Defense Threat Reduction Agency (DoD), AMDIS was developed at NIST for the critical task of verifying a major international treaty, the Chemical Weapons Convention. After more than two years of development as well as very extensive testing, it is now made available to the general analytical chemistry community. | ||
+ | |||
+ | ==== GC/MS Analysis Can Be Done "By Hand" ==== | ||
+ | |||
+ | Gas chromatography/ | ||
+ | |||
+ | ==== How Does AMDIS Differ From Conventional Analysis? ==== | ||
+ | |||
+ | This program extracts the spectrum of each component in a mixture analyzed by GC/MS or liquid chromatography/ | ||
+ | |||
+ | The overall process involves four sequential steps. | ||
+ | |||
+ | - noise analysis | ||
+ | - component perception | ||
+ | - spectral " | ||
+ | - compound identification | ||
+ | |||
+ | ==== AMDIS as a "Black Box" ==== | ||
+ | |||
+ | AMDIS can operate as a "black box" chemical identifier by displaying all identification that meets a user-selectable degree of confidence. Identification can be aided by internal standards and retention times. A performance log can be automatically maintained. | ||
+ | |||
+ | ==== AMDIS as a Advanced Analysis Tool ==== | ||
+ | |||
+ | AMDIS can also serve as a pre-processing tool for GC/MS or LC/MS data by automatically reconstructing all original component spectra down to the limits of identification for arbitrarily complex matrices. | ||
+ | |||
+ | {{: | ||
+ | |||
+ | ==== Libraries ==== | ||
+ | |||
+ | Included with AMDIS from this web page are two libraries, a chemical weapons library and a Grob mixture library. | ||
+ | |||
+ | ==== More Information ==== | ||
+ | |||
+ | {{: | ||
+ | |||
+ | {{: | ||
+ | |||
+ | [[: |