Milk SRM/D 1953 Glycan MS Library

The Milk SRM/D 1953 MS library contains tandem mass spectral data of:

• 469 positive and negative MS2 spectra of 74 oligosaccharides derived from human milk NIST Standard Reference Material 1953.
• It includes lactose, 45 neutral oligosaccharides and 29 sialylated oligosaccharides.
• All fragment ions of MS2 spectra are comprehensively annotated.
• Fragmentation techniques: HCD and FT-IT

The development of MS library of annotated oligosaccharides from human milk reference material is discussed in the manuscript.

Creating a Mass Spectral Reference Library for Oligosaccharides in Human Milk
Connie A. Remoroza, Tytus D. Mak, Maria Lorna A. De Leoz, Yuri A. Mirokhin, Stephen E. Stein
Mass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland, 20899-8362, USA
https://pubs.acs.org/doi/10.1021/acs.analchem.8b01176

For free download: https://chemdata.nist.gov/dokuwiki/doku.php?id=peptidew:lib:oligosaccarides

For questions, please contact Connie A. Remoroza (concepcion.remoroza@nist.gov)