Glycopeptide Mass Spectral Library (HCD) of Human IgG1 mAb Drugs
Over 1,700 HCD energy-dependent spectra for 81 different glycans attached to different tryptic peptide sequence motifs are contained in the glycopeptide library of human and recombinant IgG antibodies.
The library is available in a .ZIP archive as part of NIST MS Search, a full-featured Microsoft Windows® application.
Reference: J Proteome Res. 2016, 15 (5),1472-86; DOI. In-Depth Characterization and Spectral Library Building of Glycopeptides in the Tryptic Digest of a Monoclonal Antibody Using 1D and 2D LC-MS/MS. Dong Q, Yan X, Liang Y, and Stein SE.
| File | Size | Link to download | |
|---|---|---|---|
| 1 | NIST_IgG_Glycopeptide.zip - Archive for Installation of Windows Database Program and Library. Download archive and unzip installation file. Run NIST_IgG_Glycopeptide.exe to install the search program and database | ~12MB | Download |
| 2 | IgG_Glycopeptide_HCD_v1_msp.zip - Archive with library in MSP (text) format | ~1.3MB | Download |
| 3 | Readme.pdf - Short instruction for installation and use | ~214KB | Download |
| 4 | md5_checklist.chk - MD5 hash file. | 1KB | Download |
© Copyright information
These mass spectral libraries are protected by copyright law and may not be re-distributed without a valid Distribution Agreement. To receive such an agreement, contact the Standard Reference Data Program at the National Institute of Standards and Technology by emailing [email protected] or calling 301-975-2008.
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