NIST MS Search Program

What's New in the NIST MS Search Program v.2.2

This is a brief list of the new features in MS Search v.2.2 available from distributors with NIST 14.

List of features for MS Search v.2.0g can be found here

Updates to NIST MS Search v.2.2 or v2.0g are available through distributors. Updates to v.2.0f can be downloaded from this site.

These are software updates. The NIST/EPA/NIH Mass Spectral Library is NOT included in any of these downloads. A copy of the NIST/EPA/NIH Mass Spectral Library (NIST 14) is only available from distributors.

NIST MS Update Download

Demo version of MS Search and AMDIS

A demo version of the NIST MS Search Software version 2.0f and AMDIS (Automated Mass Spectral Deconvolution and Identification System) with a sample MS Databases is available. AMDIS can also be downloaded separately.


The NIST MS Search User Guide is available as a PDF files for version 14, version 11 and version 08.

Support Programs

Library conversion tool (LIB2NIST)


EPA Tandem Mass Spectrometry Starter Library of Environmentally Relevant Compounds

Instrument Specific Information

ChemStation Information

Third Party Compatibility Issues

External Site(s)

“Little” Mass Spec and Sailing