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peptidew:glycomass
Glycopeptide Mass Spectral Libraries
Libraries constructed from the analyses of intact glycopeptides derived from human IgG1 mAb drugs, human milk, SARS-CoV-2 spike, hemagglutinin and neuraminidase glycoproteins have been made available for download. For experimental details, please see publication associated with each library.
Note, human milk, SARS-CoV-2 spike, hemagglutinin and neuraminidase glycopeptide libraries include glycopeptide abundance distribution spectra (GADS). These libraries capture the distribution of glycoforms observed for a given glycosylation site and may be viewed and searched using NIST MS Search. Further, they use retention time and MS1-level information to annotate potential false positive identifications.
| Description | Associated Publication | Library Type(S) | Release/ Details |
|---|---|---|---|
| Glycan Distributions of Glycopeptides | Representing and comparing site-specific glycan abundance distributions of glycoproteins. Remoroza, Concepcion A., Burke, Meghan C., Liu, Yi, Mirokhin, Yuri A., Tchekhovskoi, Dmitrii V., Yang, Xiaoyu, Stein, Stephen E. Mass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899-8362, USA (DOI) | GADS | 07-19-2021 Details>> |
| Human IgG1 mAb Drugs | In-Depth Characterization and Spectral Library Building of Glycopeptides in the Tryptic Digest of a Monoclonal Antibody Using 1D and 2D LC-MS/MS. Dong Q, Yan X, Liang Y, and Stein E. Stein J Proteome Res. 2016, 15 (5),1472-86; DOI. | MSMS | Nov, 2015 Details>> |
| Human Milk N-linked Glycopeptides | Mass Spectra Library-Based Methods for Analysis of Site-specific N-Glycosylation Applied to Human Milk Proteins. Concepcion A. Remoroza, Meghan C. Burke, Xiaoyu Yang, Sergey Sheetlin, Yuri Mirokhin, Sanford P. Markey, Dmitrii V. Tchekhovskoi, Stephen E. Stein Mass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899-8362, USA (DOI) | MSMS GADS | 02-26-2022 Details>> |
| SARS-CoV-2 Spike Protein Glycopeptides | Determining Site-Specific Glycan Profiles of Recombinant SARS-CoV-2 Spike Proteins from Multiple Sources. Meghan C. Burke, Yi Liu, Concepcion Remoroza, Yuri A. Mirokhin, Sergey L. Sheetlin, Dmitrii V. Tchekhovskoi, Guanghui Wang, Xiaoyu Yang, Stephen E. Stein. Mass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899-8362, USA (DOI). | MSMS GADS | 04-04-2023 Details>> |
| Hemagglutinin and Neuraminidase Glycopeptides | Variation of Site-Specific Glycosylation Profiles of Recombinant Influenza Glycoproteins. Zachary C. Goecker, Meghan C. Burke, Concepcion A. Remoroza, Yi Liu, Yuri A. Mirokhin, Sergey L. Sheetlin, Dmitrii V. Tchekhovskoi, Xiaoyu Yang, Stephen E. Stein. Mass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899-8362, USA (submitted for publication). | MSMS GADS | 05-16-2023 Details>> |
peptidew/glycomass.txt · Last modified: 2024/02/08 11:58 (external edit)
