peptidew:lib:nonhumanmilk

MS Library of Free Oligosaccharides in Milk from a Variety of Mammals

The library contains

  • 2467 positive and negative ion spectra of 219 oligosaccharides derived from
    • Human milk Standard Reference Material (SRM) 1954
    • Bovine milk SRM 1549a and SRM 1849a
    • Other mammalian milk such as Asian buffalo, African lion and Saanen goat
  • Fragment ions of MS2 spectra that are comprehensively annotated
  • Fragmentation techniques: HCD and IT-FT/ion trap with FTMS

The development of MS library of annotated oligosaccharides from human milk reference material is discussed.

Increasing the coverage of a mass spectral library of milk oligosaccharides using a hybrid-search-based bootstrapping method and milks from a wide variety of mammals
Connie A. Remoroza1, Yuxue Liang1, Tytus D. Mak1, Yuri Mirokhin1, Sergey L. Sheetlin1, Xiaoyu Yang1, Joice V. San Andres2,4, Michael L. Power3, Stephen E. Stein1
1National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, MD 20899, USA
2Department of Animal Science, University of Nebraska-Lincoln, 3490 Fair St, Lincoln, NE 68583-0908, USA
3Nutrition Laboratory, Smithsonian Conservation Biology Institute, National Zoological Park, Washington, D.C., USA
4Department of Animal Science, Central Luzon State University, Maharlika Highway Nueva Ecija 3120, Philippines

Published in Analytical Chemistry
https://doi.org/10.1021/acs.analchem.0c00342

MS Library of Free Oligosaccharides in Milk from a Variety of Mammals is available for download.

File Size Link to download
1 Milk_Oligosaccharide_MS_library_2019.zip - Archive file with the Library in NIST MS Search format. Unzip whole folder where the NIST MS Search program installed. If you do not have NIST MS Search Program see Notes below. 5.9MB Download
2 Readme.pdf - Short instruction for installation and use ~341KB Download
3 md5_checklist.chk - MD5 hash file. 1KB Download

NOTES You will need NIST MS Search software v.2.3 to search the oligosaccharides library. The software can be download from here: Download installation program (32.03 MiB). Download archive and unzip installation file. Run NIST17Demo.exe to install the search program.

Release Date: December 12, 2019

For questions, please contact
Dr. Connie A. Remoroza
(email: concepcion.remoroza@nist.gov)


© Copyright information
These mass spectral libraries are protected by copyright law and may not be re-distributed without a valid Distribution Agreement. To receive such an agreement, contact the Standard Reference Data Program at the National Institute of Standards and Technology by emailing data@nist.gov or calling 301-975-2008.


peptidew/lib/nonhumanmilk.txt · Last modified: 2020/07/19 19:36 (external edit)

Page Tools