peptidew:lib:oligosaccarides

MS Library of Oligosaccharides in NIST Human Milk SRM 1953

The library contains

  • 470 positive and negative ion spectra of 74 oligosaccharides derived from human milk NIST Standard Reference Material 1953.
  • It includes lactose, 45 neutral oligosaccharides and 29 sialylated oligosaccharides.
  • All fragment ions of MS2 spectra are comprehensively annotated.
  • Fragmentation techniques: HCD and FT-IT

The development of MS library of annotated oligosaccharides from human milk reference material is discussed in the submitted manuscript.

Creating a Mass Spectral Reference Library for Oligosaccharides in Human Milk
Connie A. Remoroza, Tytus Mak, Maria Lorna A. De Leoz, Yuri A. Mirokhin, Stephen E. Stein
Mass Spectrometry Data Center, Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899-8362, USA
(Submitted)

The MS library of oligosaccharides from SRM 1953 is available for download. This mass spectral library is intended for evaluation use only to complement the submitted manuscript, which is currently under review.

File Size Link to download
1 MS_Library_of_Oligosaccharides_in_human_milk_SRM_1953.zip - Archive file with the Library in NIST MS Search format. Unzip whole folder where the NIST MS Search program installed. If you do not have NIST MS Search Program see Notes below. ~1.44MB Download
2 Readme.pdf - Short instruction for installation and use ~306KB Download
3 md5_checklist.chk - MD5 hash file. 1KB Download

NOTES

You will need NIST MS Search software v.2.3 to search the oligosaccharides library. The software can be download from here: NIST_IgG_Glycopeptide.zip. Download archive and unzip installation file. Run NISTmAb_Mass_Spectral_Library.exe to install the search program.

Release Date: March 14, 2018

For questions, please contact
Dr. Connie A. Remoroza
(email: concepcion.remoroza@nist.gov)


© Copyright information
These mass spectral libraries are protected by copyright law and may not be re-distributed without a valid Distribution Agreement. To receive such an agreement, contact the Standard Reference Data Program at the National Institute of Standards and Technology by emailing data@nist.gov or calling 301-975-2008.


peptidew/lib/oligosaccarides.txt · Last modified: 2018/03/22 15:01 (external edit)

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